永利皇宫

姓名：吴振

所在团队：畜产食品加工研究所

职称：教授/副院长

吴振，教授，博士生导师，永利皇宫-永利娱乐场 副院长，美国南佛罗里达大学医学院分子营养专业访问学者。国家高层次青年人才，浙江省杰出青年基金获得者。长期致力于乳畜产品营养组分分析与乳酸菌发酵功能因子营养健康特性研究，主要涉及乳畜制品发酵、乳酸菌株的营养及生化特性、乳酸菌肠道益生特性方面。借助畜产食品营养组分的肠道定向递送策略与肠道益生菌群的多元营养组分互作分析，挖掘营养组分-益生菌群-胃肠道-健康调节的多元互补响应机制。主持国家自然科学基金、科技部星火计划、浙江省杰出青年基金、浙江省重点研发项目等省部级项目，与宁波牛奶集团、宁波益富乐生物技术公司、乾生宁波科技有限公司、宁波老底子食品生物技术公司等多家企业建立了合作关系。近五年在食品领域国内外重要学术期刊上发表论文50余篇，其中作为第一作者发表SCI、EI收录论文30余篇；获得国家教育部科技进步一等奖1项，浙江省科技进步奖1项，宁波市科技进步奖2项，授权国内外发明专利10余项。

研究方向：

1. 乳源功能因子的精准定位与发酵乳胶体功能成分递送机制研究；

2. 区域优势益生菌株高效筛选平台建设与发酵性能功能图谱诠释；

3. SIM核心乳酸菌株表面因子菌群互作与营养代谢产物肠道微生态调节效应解析；

4. 肠道菌群等标识菌株的精准定位与营养强化复合菌剂产业化应用。

主持的科研项目或基金：

1. 国家自然科学基金面上项目2项，项目负责人；

2. 国家自然科学基金青年项目1项，项目负责人；

3. 浙江省自然科学基金杰青项目1项，项目负责人；

4. 浙江省重点研发项目1项，课题负责人；

5. 浙江省自然科学基金2项，项目负责人；

6.浙江省院士结对项目1项，项目负责人；

7. 宁波市重点研发项目1项，项目负责人。

近五年代表性论文（*通讯作者）：

1. Jianzhu Wen, Pei Cao, Guo Yang, Hangzhen Lan, Yuxing Guo, Jusheng Zheng, Zhen Wu*, Daodong Pan. Changes of the mice intestinal microbes by the oligosaccharides-enriched fermented milk in a gender-dependent pattern. Food Research International, 2021, 140.

2. Tao Zhang, Mi Su, Mingzhen Liu, Mingxuan Tao, Yao Yang, Chen Liu, Xiaoqun Zeng, Daodong Pan, Zhen Wu*, and Yuxing Guo. Optimization of Encapsulation Using Milk Polar Lipid Liposomes with S-Layer Protein and Transport Study of the ACE-Inhibitory Peptide RLSFNP. Journal of Agricultural and Food Chemistry, 2021, 69, 25, 7049-7056.

3. Fengxuan Lang, Jianzhu Wen, Zhen Wu*, Daodong Pan*, Linjun Wang. Evaluation of probiotic yoghurt by the mixed culture with Lactobacillus plantarum A3. Food Science and Human wellness, 2021, 11(2), 323-331.

4. Lei Cui, Guo Yang, Shuyi Lu, Xiaoqun Zeng, Jun He, Yuxing Guo, Daodong Pan, Zhen Wu*. Antioxidant peptides derived from hydrolyzed milk proteins by Lactobacillus strains: A BIOPEP-UWM database-based analysis. Food Research International, 2022, 156, 111339.

5. Jianzhu Wen, Yixing Yu, Mengqi Chen, Lei Cui, Qiang Xia, Xiaoqun Zeng, Yuxing Guo, Daodong Pan, Zhen Wu*. Amino Acid-Derived Quorum Sensing Molecule Alanine on the Gastrointestinal Tract Tolerance of the Lactobacillus Strains in the Cocultured Fermentation Model. Microbiology Spectrum, 2022, 10(2):e0083221.

6. Lifeng Lao, Guo Yang, Ao Zhang, Lianliang Liu, Yuxing Guo, Liwei Lian, Daodong Pan, Zhen Wu*. Anti-inflammation and gut microbiota regulation properties of fatty acids derived from fermented milk in DSS-induced colitis mice. Journal of Dairy Science, 2022, 105(10), 7865-7877.

10. Mingjuan Ou, Jiamiao Lou, Lifeng Lao, Yuxing Guo, Junwu Ji, Daodong Pan, Zhen Wu*. Plant-based meat analogue of the soybean proteins by the multi-strain solid-state mixing fermentation. Food Chemistry, 2023, 414 (15), 135671.

7. Manli Zong, Xin Tong, Muhammad Salman Farid, Chun Chang, Yuxing Guo, Liwei Lian, Xiaoqun Zeng, Daodong Pan, Zhen Wu*. Enhancement of gum Arabic/casein microencapsulation on the survival of Lactiplantibacillus plantarum in the stimulated gastrointestinal conditions. 2023, 246: 125639.

8. Muhammad Salman Farid, Rameesha Anjum, Yiping Yang, Maoling Tu, Tao Zhang, Daodong Pan, Yangying Sun*, Zhen Wu*, Recent trends in fermented plant-based analogues and products, bioactive peptides, and novel technologies-assisted fermentation. Trends in Food Science & Technology. 2024: 104529.

9. Yu Liang, Chun Chang, Ting Jiang, Ting Zheng, Youwei Ji, Yuxing Guo, Daodong Pan, Tao Zhang, Zhen Wu*, Antioxidant Peptides Derived from Cheese Products via Single and Mixed Lactobacillus Strain Fermentation. Journal of Agricultural and Food Chemistry.2024,72(38):21221-21230.

授权发明专利

1. 一种乳酸菌、筛选及应用, ZL201911127323.6

2. 一种复合发酵菌剂及其在制备发酵乳中的应用, ZL202110565741.4

3. 一种功能性嗜酸乳杆菌黏液结合蛋白的表达纯化及其应用, ZL201811299290.9

4. 实时荧光定量PCR检测乳酸菌luxS基因的引物组及其应用, ZL202110567554.X

5. 一种功能性嗜酸乳杆菌肽聚糖的制备方法及其抗炎活性应用, ZL201410156383.1

6. 一种富多种功能因子水蜜桃花生复合风味酸奶及其制备方法, ZL201910554305.X

7. 一种植物蛋白人造肉及其制备方法, ZL202210634074.5

8. 一种基于乳酸菌LPxTG基序重组蛋白的构建及应用, ZL202111491733.6

9. 一种松花风味功能性发酵香肚及其制备方法, ZL201510104307.0

联系方式：

通信地址：浙江省宁波市北仑区梅山七星南路169号

邮箱： [email protected]